They publish a comprehensive genetic analysis of glioblastoma
posted in Cancer |The Research Network Cancer Genome Atlas published today in the British science journal “Nature” a “comprehensive” analysis of the genetic causes of glioblastoma, one of the most aggressive brain tumors.
In this study, one that will compose the “pilot project” of the Atlas data are detailed genetic information from individuals with this cancer.
Among them, the sequence of nucleotides, the number of copies of genes, their expression and alterations in DNA methylation (replacement of hydrogen atoms by methyl groups).
During its investigation, the investigator consortium formed by dozens of institutions, especially United States-has found, for example, those three genes, ERBB2, NF1 and TP53-play an important role in glioblastoma.
He has also discovered unknown mutations in the kinases regulatory subunit gene PIK3R1.
With this work, scientists try to give an overview of the signs that the cancer is going to broadcast as it develops in the body.
Apart from its publication in “Nature”, information on glioblastoma, a cancer sufferer U.S. Senator Ted Kennedy, will also appear in the journal “Science”